专利名称：Protein knobs
发明人：William R. Moyle,Yongna Xing申请号：US10797553申请日：20040310
公开号：US20060177894A1公开日：20060810
摘要：Compositions containing a knob attached to a specific site of a protein andmethods of producing and using these compositions are disclosed. The compositionscomprise a knob, a tail portion and a protein portion. The protein portion contains asubstituted cysteine residue at the desired location of labeling. The tail portion is locatedat the terminal end of the protein portion. The knob is linked to the end of the tailportion and contains a cysteine residue. The substituted cysteine residue on the proteinportion and the cysteine residue on the knob form a disulfide bond, thereby tagging theprotein portion at the desired site with the knob.
申请人：William R. Moyle,Yongna Xing
地址：Piscatawy NJ US,Edison NJ US
国籍：US,US
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